Table 2.
The number of clones predicted with artificial mutation profiles
| ID | Method | J = 1 | J = 2 | J = 3 | J = 4 | J = 5 |
|---|---|---|---|---|---|---|
| WGS-1 | SigTracer | 16 | 81 | 3 | 0 | 0 |
| CloneSig | 1 | 25 | 42 | 23 | 8 | |
| WGS-2 | SigTracer | 87 | 13 | 0 | 0 | 0 |
| CloneSig | 23 | 44 | 22 | 10 | 1 | |
| WGS-3 | SigTracer | 6 | 72 | 21 | 1 | 0 |
| CloneSig | 0 | 12 | 39 | 35 | 14 | |
| WGS-4 | SigTracer | 0 | 63 | 32 | 5 | 0 |
| CloneSig | 1 | 7 | 36 | 38 | 18 | |
| WGS-5 | SigTracer | 23 | 77 | 0 | 0 | 0 |
| CloneSig | 0 | 30 | 49 | 20 | 1 | |
| WGS-6 | SigTracer | 19 | 80 | 1 | 0 | 0 |
| CloneSig | 1 | 31 | 43 | 19 | 6 | |
| WGS-7 | SigTracer | 7 | 91 | 2 | 0 | 0 |
| CloneSig | 0 | 25 | 49 | 21 | 5 | |
| WES-1 | SigTracer | 12 | 82 | 6 | 0 | 0 |
| CloneSig | 1 | 21 | 27 | 17 | 34 | |
| Ideal-1 | SigTracer | 0 | 20 | 78 | 2 | 0 |
| CloneSig | 0 | 0 | 21 | 30 | 49 | |
| Ideal-2 | SigTracer | 0 | 8 | 50 | 39 | 3 |
| CloneSig | 0 | 0 | 7 | 29 | 64 |
All IDs indicate the name of simulation datasets which are provided in Table 1. Columns with J = 1 ∼ 5 indicate the number of samples whose estimated numbers are J. Out of the 100 samples in each dataset, the bold characters indicate the number of samples for which the correct number of clones could be estimated by each method.