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Intraoperative imaging of glioblastoma using a fluorescence surgical microscope and correlated mapping with preoperative MRI and neuronavigation. Red PpIX fluorescence signal is visible in the bulk tumor (A), located intraoperatively using neuronavigation (B). No detectable PpIX fluorescence was seen in the tumor margin (C), identified using neuronavigation and preoperative MRI (D).
