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. 2021 Nov 1;18:251. doi: 10.1186/s12974-021-02301-0

Table 2.

Association between baseline anti-GM1 and anti-GD1a antibodies and prognostic

Univariate and Multivariable logistic analysis for inability to walk independently at 6 months
Variable OR 95% CI p
Univariate analysis
GM1 IgG 3.2 1.05–9.71 0.04
GD1a IgG 0.48 0.05–4.24 0.515
logNFL 3.22 1.46–7.14 0.004
AMAN 2.97 0.73–12.07 0.127
Diarrhoea 3.64 1.21–10.91 0.021
Age 1.05 1.01–1.10 0.005
Initial GDS 3.15 1.38–7.18 0.006
Multivariable logistic analysis
logNfL 3.13 1.27–7.67 0.012
Age 1.05 1.01–1.10 0.013
Univariate and Multivariable logistic analysis for inability to walk independently at 1 year
Variable OR 95% CI p
Univariate analysis
GM1 IgG 5.09 1.38–18.73 0.014
GD1a IgG 0.92 0.10–8.44 0.944
logNFL 3.11 1.27–7.55 0.012
AMAN 1.475 0.27–7.97 0.652
Diarrhoea 2.7 0.74–9.82 0.131
Age 1.06 1.01–1.11 0.014
Initial GDS 2.79 1.12–6.93 0.027
Multivariable logistic analysis
GM1 IgG 6.98 1.60–30.36 0.01
Age 1.07 1.01–1.12 0.01
Univariate and Multivariable logistic analysis for inability to run independently at 1 year
Variable OR 95% CI p
Univariate analysis
GM1 IgG 4.16 1.39–12.49 0.011
GD1a IgG 0.72 0.13–3.99 0.710
logNFL 4.37 1.95–9.78  < 0.0001
AMAN 6.53 1.57–27.17 0.01
Diarrhoea 2.33 0.83–6.57 0.109
Age 1.04 1.01–1.07 0.023
Initial GDS 1.81 1.08–3.04 0.025
Multivariable logistic analysis
Age 1.04 1.01–1.08 0.022
AMAN 6.19 1.01–38.02 0.049
logNfL 3.17 1.34–7.50 0.009

logNfL log-transformed neurofilament light chain; AMAN acute motor axonal neuropathy; GDS Guillain–Barré Syndrome Disability Score