Table 2.
Biochemical analysis of plasma in HFD-induced obese mice
| Profile | Group |
|||||
|---|---|---|---|---|---|---|
| ND1 | HFD2 | HFD + LAB strain (2 × 108 CFU/mouse) |
||||
| MG4502 | MG4524 | MG5149 | MG5285 | |||
| AST (IU/L) | 134.0 5 ± 73.85c | 384.7 ± 81.47a | 186.93 ± 80.96b | 51.40 ± 17.94b | 54.60 ± 29.14b | 49.86 ± 13.11b |
| ALT (IU/L) | 37.35 ± 10.27b | 81.95 ± 21.18a | 49.30 ± 9.75b | 51.40 ± 17.94b | 54.60 ± 29.14b | 49.86 ± 13.11b |
| TG (mg/dL)3 | 12.19 ± 2.96d | 62.16 ± 15.39a | 44.44 ± 12.20b | 38.58 ± 6.57bc | 30.39 ± 14.04c | 30.00 ± 10.29c |
| TCH (mg/dL)4 | 107.79 ± 6.37c | 172.4 ± 21.56a | 150.75 ± 7.54b | 143.16 ± 16.94b | 143.80 ± 21.34b | 138.11 ± 12.29b |
| HDL-c (mg/dL) | 54.54 ± 3.54c | 67.09 ± 3.17a | 65.65 ± 2.55ab | 61.70 ± 4.72b | 62.73 ± 4.25b | 63.50 ± 3.72ab |
| LDL-c (mg/dL) | 4.86 ± 0.81e | 10.70 ± 1.88a | 8.16 ± 0.93bc | 8.51 ± 1.58b | 6.95 ± 1.49cd | 6.48 ± 1.17d |
| HDL-c/TCH (%) | 50.70 ± 3.21a | 39.42 ± 5.01c | 43.65 ± 2.92b | 43.33 ± 2.65bc | 44.12 ± 4.18b | 46.27 ± 4.69b |
| Glucose (mg/dL) | 247.84 ± 23.54bcd | 303.83 ± 43.64a | 275.33 ± 14.13ab | 255.77 ± 29.01abc | 240.04 ± 29.34cd | 228.67 ± 25.82d |
| Leptin (ng/mL) | 3.85 ± 1.44c | 52.00 ± 4.83a | 31.08 ± 5.19b | 34.61 ± 8.69b | 28.90 ± 8.88b | 29.59 ± 6.33b |
| Adiponectin (μg/mL) | 152.70 ± 14.89a | 93.42 ± 7.85d | 123.7 ± 17.01bc | 112.5 ± 17.01c | 127.8 ± 12.04b | 135.10 ± 11.51b |
1
ND: normal-diet
2
HFD: high-fat-diet
3
TG: triglyceride
4
TCH: total cholesterol. Results are presented as the mean ± SD (n = 6). Different letters indicate significant differences between means at p < 0.05 by Duncan’s multiple range test.