Fig. 3.

Aβ aggregation and phosphorylation of Tau Associated Protein Expression in young APP/PS1 mice, protein expression of IDE, ADAM10, BACE1, Cathepsin B, P-Tau ser396, and P-Tau ser404 in the hippocampus (a) and cortex (b) were detected by western blotting. In middle-aged APP/PS1 mice, the above proteins were shown in the hippocampus (c) and cortex (d) via western blotting. All values were presented as mean + SEM. A.U. means arbitrary units. Representative blots were shown in the right panel in a–d.