TABLE 1.
The number of differentially enriched cell populations across four gene signature sources in at least 1 dataset (TCGA microarray, GSE10358, and GSE13159).
| Gene Signatures | Angelova | Bindea | Charoentong | Senbabaoglu | Sum |
|---|---|---|---|---|---|
| Up‐regulated in high B7‐H3 | |||||
| Macrophage | 2 | 2 | 2 | 2 | 8 |
| Neutrophil | 2 | 2 | 2 | 2 | 8 |
| Dendritic cell | 2 | 2 | 1 | 3 | 8 |
| Type 17 T helper cell | 2 | 2 | 2 | 2 | 8 |
| CD56dim natural killer cell | 1 | 1 | 2 | 1 | 5 |
| Monocytes | 1 | 0 | 3 | 0 | 4 |
| Mast cell | 1 | 0 | 2 | 0 | 3 |
| MDSC | 1 | 0 | 2 | 0 | 3 |
| Regulatory T cell | 0 | 0 | 2 | 0 | 2 |
| Down‐regulated in high B7‐H3 | |||||
| Memory B cell | 3 | 0 | 3 | 0 | 6 |
| B cell | 0 | 1 | 0 | 2 | 3 |
| T helper cell | 0 | 1 | 0 | 2 | 3 |
| Activated CD4 T cell | 1 | 0 | 1 | 0 | 2 |
| Effector memory CD4 T cell | 1 | 0 | 1 | 0 | 2 |
| Activated CD8 T cell | 1 | 0 | 0 | 0 | 1 |
| Natural killer cell | 0 | 0 | 0 | 1 | 1 |