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Boosting of antibody response to the stem of HA during prime vaccination with adjuvanted H5N1 vaccine and lack of boosting after the boost vaccination. Filled triangles and open triangles are the responses to the stem of HA after prime and boost vaccinations, respectively. Prevaccination immunity reduces the boost, and the relationship is approximately linear on log-log plot. (Figure created from data in Ellebedy et al. 2020.)
