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. Author manuscript; available in PMC: 2021 Nov 1.
Published in final edited form as: ACS Infect Dis. 2019 Jul 10;5(9):1590–1596. doi: 10.1021/acsinfecdis.9b00134

Scheme 1.

Scheme 1

a) Preparation of NCs loaded with different phytochemicals. DTDS, the biodegradable crosslinker, was dissolved in the selected phytochemical. This resulting oil solution was then emulsified into water in the presence of PONI-GMT to form cross-linked polymer-stabilized nanocomposites. This delivery strategy demonstrated improved antimicrobial activity against bacterial biofilms; b) Chemical structure of PONI-GMT; c) Chemical structure of DTDS; d) Cross-linked structure of NCs.