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. Author manuscript; available in PMC: 2022 May 1.
Published in final edited form as: J Biomed Inform. 2021 Mar 11;117:103719. doi: 10.1016/j.jbi.2021.103719

Table 6.

This table shows AUROC statistics from several EHR-based drug safety studies. Because these studies used different subsets of the reference dataset, the comparisons are not strictly comparable. Also note that all of the studies used exclusively EHR data as the primary source of empirical data, except for [104], which incorporated other sources of empirical data including claims and FAERS-derived data to attain a higher adjusted score, pointing to a promising potential area of future drug safety research.

Study Li (2014) Li (2015) Malec (2016) Malec (2018) This study
Naive 0.53 0.51 0.53 0.504 0.55
Adjusted 0.51 (lasso) 0.89 (meta-analysis) 0.55 0.58 0.65