. Author manuscript; available in PMC: 2021 Nov 1.

Published in final edited form as: J Am Coll Cardiol. 2019 Jun 18;73(23):3006–3017. doi: 10.1016/j.jacc.2019.04.015

TABLE 1.

Baseline-Adjusted Fall in ABPM

	24-h ABPM
Trial	Systolic	p Value	Diastolic	p Value
SPYRAL HTN-ON MED	−7.0 mm Hg (−12.0 to −2.1)	0.0059	−4.3 mm Hg (−7.8 to −0.8)	0.0174
RADIANCE-HTN SOLO	−7.0 ± 8.6 mm Hg (−7.1 to −1.2)	0.006	− 4.4 ± 5.8 mm Hg (−3.7 to −0.2)	0.07
SPYRAL HTN-OFF MED	−5.3 mm Hg (−8.6 to −2.0)	0.0020	−4.8 mm Hg (−6.8 to −2.8)	0.001

Values are mean (95% confidence interval) or mean ± SD (95% confidence interval).

ABPM = ambulatory blood pressure measurements; CI = confidence interval; RADIANCE-HTN SOLO = Endovascular ultrasound renal denervation to treat hypertension (RADIANCE-HTN SOLO): a multicenter, international, single-blind, randomized, sham-controlled trial; SPYRAL HTN-ON MED = Effect of renal denervation on blood pressure in the presence of antihypertensive drugs: 6-month efficacy and safety results from the SPYRAL HTN-ON MED proof-of-concept randomized trial; SPYRAL HTN-OFF MED = Catheter-based renal denervation in patients with uncontrolled hypertension in the absence of antihypertensive medications (SPYRAL HTN-OFF MED): a randomized, sham-controlled, proof-of-concept trial.