Table AP-2.

Ranking the impact of each feature on the DNN model.

Method	First dataset [2]	Second dataset (OSR dataset) [6]	Third dataset [9]	Third balanced dataset
ELI5	1. AST	1. Suspect	1. Leukocytes	1. Leukocytes
	2. CRP	2. LDH	2. Platelets	2. Platelets
	3. AGE	3. Age	3. Eosinophils	3. Monocytes
	4. WBC	4. PCR	4. Monocytes	4. Eosinophils
	5. LDH	5. BAT	5. C reactive protein	5. Patient age quantile
	6. GENDER	6. BA	6. Patient age quantile	6. C reactive protein
	7. Eosinophils	7. CA	7. Red blood Cells	7. Red blood Cells
	8. ALT	8. EO	8. Neutrophils	8. Hematocrit
	9. Lymphocytes	9. EOT	9. Hematocrit	9. Hemoglobin
	10. Neutrophils	10. WBC	10. Lymphocytes	10. Lymphocytes
	11. Platelets	11. LYT	11. Basophils	11. Basophils
	12. Monocytes	12. MOT	12. Hemoglobin	12. Creatinine
	13. Basophils	13. AST	13. Creatinine	13. Neutrophils
	14. GGT	14. NET	14. Aspartate transaminase	14. Potassium
	15. ALP	15. MO	15. Potassium	15. Urea
		16. ALT	16. Alanine transaminase	16. Sodium
		17. RBC	17. Urea	17. Aspartate transaminase
		18. HGB	18. Sodium	18. Alanine transaminase
		19. NAT	19. Serum Glucose	19. Serum Glucose
		20. NE
		21. HCT
		22. LY
		23. GLU
		24. MCV
		25. PLT1
		26. GGT
		27. MCHC
		28. CREA
		29. UREA
		30. MCH
		31. ALP
		32. KAL
		33. CK
		34. Sex
LIME	1. AST	1. LDH	1. Leukocytes	1. Leukocytes
	2. LDH	2. BAT	2. Eosinophils	2. Eosinophils
	3. GENDER	3. Suspect	3. Platelets	3. Monocytes
	4. Lymphocytes	4. CA	4. Patient age quantile	4. Platelets
	5. WBC	5. AST	5. Creatinine	5. Patient age quantile
	6. CRP	6. PCR	6. Basophils	6. Creatinine
	7. Neutrophils	7. WBC	7. Alanine transaminase	7. Red blood Cells
	8. Eosinophils	8. EOT	8. Lymphocytes	8. Hemoglobin
	9. Basophils	9. BA	9. Potassium	9. Sodium
	10. ALT	10. EO	10. Serum Glucose	10. C reactive protein
	11. Platelets	11. RBC	11. Monocytes	11. Basophils
	12. AGE	12. NET	12. Hemoglobin	12. Hematocrit
	13. GGT	13. HCT	13. Hematocrit	13. Potassium
	14. Monocytes	14. LYT	14. Aspartate transaminase	14. Urea
	15. ALP	15. MOT	15. Red blood Cells	15. Neutrophils
		16. HGB	16. Sodium	16. Serum Glucose
		17. CK	17. Urea	17. Lymphocytes
		18. ALT	18. C reactive protein	18. Aspartate transaminase
		19. GGT	19. Neutrophils	19. Alanine transaminase
		20. Age
		21. Sex
		22. NAT
		23. GLU
		24. NE
		25. KAL
		26. PLT1
		27. MO
		28. MCH
		29. UREA
		30. ALP
		31. MCV
		32. MCHC
		33. CREA
		34. LY
SHAP	1. WBC	1. WBC	1. Leukocytes	1. Leukocytes
	2. CRP	2. HGB	2. Eosinophils	2. Monocytes
	3. GENDER	3. Suspect	3. Monocytes	3. Eosinophils
	4. ALT	4. RBC	4. Patient age quantile	4. C reactive protein
	5. LDH	5. CA	5. Platelets	5. Aspartate transaminase
	6. Neutrophils	6. EOT	6. C reactive protein	6. Patient age quantile
	7. Platelets	7. PCR	7. Neutrophils	7. Red blood Cells
	8. AGE	8. Sex	8. Lymphocytes	8. Hematocrit
	9. Eosinophils	9. MCV	9. Potassium	9. Lymphocytes
	10. Monocytes	10. LY	10. Hematocrit	10. Neutrophils
	11. Basophils	11. Age	11. Red blood Cells	11. Serum Glucose
	12. Lymphocytes	12. MCHC	12. Basophils	12. Potassium
	13. GGT	13. BA	13. Hemoglobin	13. Hemoglobin
	14. AST	14. NE	14. Creatinine	14. Alanine transaminase
	15. ALP	15. NET	15. Aspartate transaminase	15. Platelets
		16. ALT	16. Alanine transaminase	16. Creatinine
		17. AST	17. Serum Glucose	17. Basophils
		18. LYT	18. Urea	18. Sodium
		19. PLT1	19. Sodium	19. Urea
		20. HCT
		21. LDH
		22. EO
		23. MO
		24. KAL
		25. NAT
		26. BAT
		27. MCH
		28. UREA
		29. CREA
		30. GLU
		31. ALP
		32. MOT
		33. GGT
		34. CK