Abstract
Sulphur metabolism was studied in thymuses of 8 young dogs stressed by peripheral irradiation. Autoradiographic studies revealed a significantly heavier uptake of 35S in the medulla, rich in reticular cells, than in the cortex (t = 9.556, P = 0.001). In epithelial cysts in the thymus the uptake of 35S was so dense that it appeared as black areas. Possibility of sulphur-containing secretion was discussed.
Keywords: thymus, reticular cells, epithelial cysts, 35S, irradiation
Sammanfattning
Svavelomsättningen in thymus från 8 unga hundar, vilka stressats med perifer bestrålning, har undersökts. Autoradiografiskt kunde visas starkare ansamling av 35S i medullan, som är rik på retikulära celler, än i cortex. I thymus’ epiteliala cystor var 35S ansamlingen så stark, att denna sågs som svara fläckar. En eventuell svavehaltig thymussekretion diskuteras.
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References
- Arnesen Kr. The secretory apparatus in the thymus of mice. Acta path, microbiol. scand. 1958;43:339–349. doi: 10.1111/j.1699-0463.1958.tb04670.x. [DOI] [PubMed] [Google Scholar]
- Clark, S. L.: Cytological evidence of secretion in the thymus. Thymus, Experimental and Clinical Studies. A Giba Foundation Symposium. J. A. Churchill Ltd. London 1966, 3–30.
- Comsa J. Influence de l’hormone thymique sur la consommation de glycose du diaphragme du rat. (Influence of thymic hormone on the consumption of glycogen in rat diaphragm muscle) Ann. Endocr. (Paris) 1965;26:472–475. [PubMed] [Google Scholar]
- Diderholm H, Hellman B. Nature and metabolism of a thymus cyst studied by histochemistry and autoradiography. Z. Zellforsch. 1958;48:450. doi: 10.1007/BF00339713. [DOI] [PubMed] [Google Scholar]
- ver Eecke A. Structure et modification fonctionelles du thymus de la grenouille. (Structure and functional alterations in frog thymus) Bull. Acad. roy. Med. Belg. 1899;13:67–86. [Google Scholar]
- Fischer, R. A.: Statistical methods for research workers. Oliver & Boyd, Edinburgh 1950.
- Glucksmann A, Cherry C P. The effect of castration, oestrogens, testosterone and the oestrous cycle on the cortical epithelium of the thymus in male and female rats. J. Anat. (Lond.) 1968;103:113–133. [PMC free article] [PubMed] [Google Scholar]
- van Haelst U. Light and electron microscopic study of the normal and pathological thymus of the rat. I. The normal thymus. Z. Zellforsch. 1967;77:534–553. doi: 10.1007/BF00319347. [DOI] [PubMed] [Google Scholar]
- Khussar Yu P. Reaction of epithelium of thymus to introduction of foreign body following X-ray irradiation. Arkh. Anat. Gistol. Embriol. 1964;47:96–101. [PubMed] [Google Scholar]
- Kostowiecki M. Secretory component in the thymus of the pregnant white rats. Z. mikr.-anat. Forsch. 1967;79:141–183. [PubMed] [Google Scholar]
- Oksanen A. A histological and histochemical study on the epithelial rosettes and cysts in the thymus of the rat. Acta histochem. (Jena) 1966;25:267–275. [PubMed] [Google Scholar]
- Oksanen A. The thymus of the adult stressed dog, a predominantly epithelial organ. Acta path. microbiol. scand. 1968;72:192–204. doi: 10.1111/j.1699-0463.1968.tb01335.x. [DOI] [PubMed] [Google Scholar]
- Oksanen, A. & O. Tuurala: The thymus, a lymphatic and epithelial organ of the snake (Vipera berus). Anat. Anz. 1970, 126, 400– 410. [PubMed]
- Pansky B, House E L, Cone L A. An insulin-like thymic factor. A preliminary report. Diabetes. 1965;14:325–332. doi: 10.2337/diab.14.6.325. [DOI] [PubMed] [Google Scholar]
- Szent-Györgyi A, Hegyeli A, McLaughlin J A. Constituents of the thymus gland and their relation to growth fertility, muscle, and cancer. Proc. nat. Acad. Sci. (Wash.) 1962;48:1439–1442. doi: 10.1073/pnas.48.8.1439. [DOI] [PMC free article] [PubMed] [Google Scholar]
