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. 2021 Oct 18;11:753119. doi: 10.3389/fonc.2021.753119

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Copyright © 2021 Liao, Qian, Zhang, Tao, Li, Zhang, Liang, Li, Xie, Zhuo, Chen, Jiang, Cao, Niu, Xue, Ni, Pan and Cui

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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ARV-825 suppresses the viability of gastric cancer cells. (A) BET protein levels in gastric cancer cells. (B) Viability of gastric cancer cells treated with ARV-825 at different concentrations. Values of IC50 have been calculated and shown on the graph. (C) Chemical structures of ARV-825, OTX015, and JQ1. (D) The cell viability of MGC803, HGC27, AGS, and SGC7901 cells treated with ARV-825, OTX015, and JQ1. (E) Morphology of MGC803, HGC27, AGS, and SGC7901 cells treated with ARV-825.