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. 2021 Oct 18;11:753119. doi: 10.3389/fonc.2021.753119

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Copyright © 2021 Liao, Qian, Zhang, Tao, Li, Zhang, Liang, Li, Xie, Zhuo, Chen, Jiang, Cao, Niu, Xue, Ni, Pan and Cui

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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ARV-825 degrades BET proteins in gastric cancer cells. (A) ARV-825 robustly degraded BET protein and induced caspase 3 and PARP cleavage in MGC803 and HGC27 cells. (B) ARV-825 robustly degraded BET protein and induced caspase 3 and PARP cleavage in AGS and SGC7901 cells.