Table 5.
Generalized Linear Modeling Analyses for the Mean age of ALS Diagnosis by frequency of Vigorous Physical Activity and age, among US adults with ALS who responded to the National ALS Registry’s Physical Activity Survey (October 19, 2010–December 31, 2018)
Unadjusted Model | Adjusted Model * | |||||||
---|---|---|---|---|---|---|---|---|
| ||||||||
Variable | Parameter Estimate | Mean Age of ALS Diagnosis | t Value | Pr > |t| | Parameter Estimate | Mean Age of Diagnosis | t Value | Pr > |t| |
Reported Age of VPA ^ | ||||||||
Ages 15 – 24 years | −3.7231 | 57.8 | −11.12 | <0.0001 | −1.2133 | 58.5 | −3.31 | 0.0009 |
Ages 25 – 34 years | −3.2222 | 57.9 | −10.5 | <0.0001 | −0.0722 | 59.6 | −2.45 | 0.0144 |
Ages 35 – 44 years | −1.2556 | 58.9 | −4.43 | <0.0001 | −0.0123 | 59.9 | −0.04 | 0.965 |
Ages 45 – 54 years | −0.8486 | 61.2 | −3.3 | 0.001 | 0.1742 | 61.5 | 0.69 | 0.4902 |
Ages 55 – 64 years | 0.0842 | 65.5 | 0.35 | 0.7257 | 0.2453 | 65.5 | 1.03 | 0.3053 |
- Adjusted model, controlling for year of birth, gender, weight change, BMI, race, military status, physically active job, and site of onset
VPA is moderate or heavy - at least 3 sessions per week, compared to less than 3 sessions per week