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. 2021 Oct 18;11:743540. doi: 10.3389/fonc.2021.743540

Table 3.

The association between tumor-infiltrating CD8+ CTLs, CD163+ M2 TAMs, Foxp3+ Tregs and clinicopathological features.

CD8+ CTL CD163+ M2 macrophage Foxp3+ Treg
median (IQR) P median (IQR) P median (IQR) P
Age 0.700 0.108 0.854
<55 N=30 46 (34, 65) 92 (71, 117) 50 (29,83)
≥55 N=40 49 (23, 73) 113 (84, 149) 52 (29, 92)
Gender 0.667 0.914 0.872
male N=52 45 (27, 67) 100 (85, 134) 52 (30, 82)
female N=18 52 (19, 73) 104 (64, 157) 47 (26, 104)
differentiation, n (%) 0.321 0.343 0.955
poor/moderate N=48 45 (25, 64) 99 (78, 134) 53 (28, 95)
well N=22 57 (26, 104) 118 (81, 156) 46 (31, 78)
Histological type, n (%) 0.295 0.896 0.266
ulcerative 55 (35, 68) 99 (72, 143) 53 (30, 96)
N=39
other N=31
40 (23, 64) 102 (87, 138) 48 (25, 70)
T stage 0.431 0.750 0.644
T3 N=47 42 (27, 65) 101 (85, 143) 53 (33, 81)
T4 N=23 53 (25, 89) 99 (76, 138) 43 (25, 103)
N stage 0.260 0.026 0.418
N0 N=24 39 (17, 73) 89 (67, 116) 42 (25, 77)
N+ N=46 52 (29, 64) 108 (85, 145) 53 (30, 95)