Table 4.
Logistic regression analysis of immunological and clinicopathological features with respect to LACR patients’ clinical response to nCRT.
| Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|
| OR | 95%Cl | p-value | OR | 95%Cl | p-value | |
| CD8 | 1.030 | 1.011~1.048 | 0.002 | 1.042 | 1.015~1.070 | 0.002 |
| CD163 | 0.975 | 0.955~0.995 | 0.015 | 0.969 | 0.941~0.998 | 0.036 |
| FoxP3 | 0.982 | 0.962~1.002 | 0.070 | 0.978 | 0.949~1.007 | 0.139 |
| Age <55 ≥55 |
1.000 1.435 |
0.443~4.647 |
0.547 |
1.000 0.485 |
0.065~3.608 |
0.480 |
| Gender male female |
1.000 0.745 |
0.183~3.044 |
0.682 |
1.000 0.677 |
0.099~4.632 |
0.691 |
| differentiation poor/moderate well |
1.000 1.875 |
0.561~6.268 |
0.307 |
1.000 1.174 |
0.141~9.770 |
0.882 |
| Histological type ulcerative other |
1.000 1.075 |
0.330~3.508 |
0.904 |
1.000 2.478 |
0.315~19.484 |
0.389 |
| cT stage cT3 cT4 |
1.000 0.711 |
0.201~2.515 |
0.597 |
1.000 0.728 |
0.097~5.486 |
0.758 |
| cN stage cN0 cN+ |
1.000 2.294 |
0.696~7.560 |
0.172 |
1.000 4.476 |
0.531~37.763 |
0.168 |
| chemotherapy with oxaliplatin without oxaliplatin |
1.000 2.759 |
0.681~11.175 |
0.155 |
1.000 6.236 |
0.622~62.529 |
0.120 |