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. 2021 Oct 28;14:1579–1591. doi: 10.2147/CCID.S335440

Table 6.

Demographic Characteristics and Intake of Nutrients and Foods in Alopecia Areata (AA) Groups with and without Atopic Dermatitis (AD)

AA without AD (n = 54) AA with AD (n = 16) p values
Sex Male 13 Male 6 0.343c
Female 41 Female 10
Age (years)a 51.59 ± 16.60 37.50 ± 11.96 0.00239**
SALTb 6 (2–17.5) 8 (3–41.5) 0.556
Body mass index (kg/m2)b 21.69 (19.43–23.93) 22.28 (20.35–24.53) 0.321
Energy intake (kcal/day)b 1595 (1326–1995) 1789 (1221–2047) 0.321
Nutrients
Animal protein (% energy)b 8.59 (6.68–10.28) 9.30 (7.19–10.16) 0.506
Vegetable protein (% energy)a 6.49 ± 1.20 6.25± 1.14 0.485
Animal fat (% energy)a 12.44 ± 4.39 14.16 ± 4.53 0.177
Vegetable fat (% energy)b 15.22 (13.14–18.33) 15.22 (13.87–16.04) 0.905
Carbohydrate (% energy)a 51.39 ± 8.91 51.63 ± 6.85 0.921
Na (mg/kcal)b 2.27 (2.03–2.65) 2.26 (2.14–2.57) 0.785
K (mg/kcal)b 1.302 (1.128–1.635) 1.255 (1.135–1.544) 0.534
Ca (μg/kcal)b 273.5 (226.8–347.5) 268.2 (190.9–347.1) 0.498
Mg (μg/kcal)b 130.6 (116.3–161.6) 114.7 (108.1–141.1) 0.196
Pi (μg/kcal)b 552.2 (478.3–652.5) 553.3 (449.7–636.9) 0.764
Fe (μg/kcal)b 4.08 (3.49–5.13) 4.02 (3.27–4.55) 0.506
Zn (μg/kcal)a 4.295 ± 0.899 4.4769 ± 0.776 0.468
Cu (μg/kcal)b 0.582 (0.520–0.698) 0.587 (0.506–0.606) 0.48
Mn (μg/kcal)b 1.67 (1.35–2.38) 1.57 (1.16–2.21) 0.571
Retinol (μg/kcal)b 0.173 (0.134–0.285) 0.197 (0.145–0.306) 0.515
β-carotene (μg/kcal)b 1.923 (1.068–3.184) 2.052 (1.326–2.487) 0.828
Vitamin D (ng/kcal)b 5.512 (3.798–9.029) 4.957 (2.305–7.019) 0.291
α-tocopherol (μg/kcal)a 4.408 ± 1.162 4.154 ± 0.818 0.418
Vitamin K (μg/kcal)b 0.140 (0.107–0.251) 0.115 (0.096–0.158) 0.164
Vitamin B1 (μg/kcal)a 0.429 ± 0.120 0.438 ± 0.099 0.780
Vitamin B2 (μg/kcal)b 0.715 (0.591–0.862) 0.722 (0.624–0.864) 0.994
Niacin (μg/kcal)a 9.865 ± 2.857 9.304 ± 1.871 0.463
Vitamin B6 (μg/kcal)b 0.715 ± 0.222 0.666 ± 0.184 0.432
Vitamin B12 (ng/kcal)b 3.91 (3.18–5.89) 4.37 (2.72–5.72) 0.961
Foric acid (μg/kcal)b 0.180 (0.150–0.238) 0.166 (0.137–0.207) 0.413
Panthotenic acid (μ/kcal)b 3.493 (3.029–4.032) 3.574 (2.856–3.981) 0.883
Vitamin C (μg/kcal)b 62.20 (51.09–90.01) 52.74 (39.01–80.83) 0.186
SFA (% energy)a 7.384 ± 1.986 8.311 ± 2.309 0.119
MUFA (% energy)a 9.995 ± 2.531 10.570 ± 1.708 0.398
n-3PUFA (% energy)a 1.333 ± 0.396 1.207 ± 0.296 0.241
n-6PUFA (% energy)a 5.550 ± 1.404 5.371 ± 0.791 0.627
Cholesterol (μg/kcal)a 203.87 ± 74.50 231.06 ± 67.23 0.195
Dietary fiber (mg/kcal)b 6.476 (5.059–7.918) 5.908 (4.417–6.838) 0.304
Alcohol (% energy)b 0 (0–5.418) 0.537 (0–2.484) 0.703
Foods
Cereals (mg/kcal)a 181.31 ± 68.59 203.74 ± 48.28 0.227
Potatoes (mg/kcal)b 15.36 (9.67–28.81) 30.40 (10.45–45.07) 0.184
Pulses (mg/kcal)b 2.015 (1.277–4.725) 2.127 (1.406–3.024) 0.916
Green and yellow vegetables (mg/kcal)b 56.33 (29.82–90.96) 58.32 (38.64–78.10) 0.817
Other vegetables (mg/kcal)a 90.01 ± 44.61 86.60 ± 49.59 0.794
Fruit (mg/kcal)b 72.13 (23.39–134.11) 46.38 (24.75–75.47) 0.193
Fish and shellfish (mg/kcal)b 31.64 (22.63–48.94) 26.53 (20.11–40.47) 0.338
Meat (mg/kcal)b 40.06 (25.38–55.42) 47.94 (41.88–58.79) 0.0974
Eggs (mg/kcal)b 19.33 (12.04–27.19) 25.80 (16.03–31.36) 0.254
Dairy products (mg/kcal)b 74.08 (27.17–114.80) 68.38 (21.38–92.55) 0.600
Oils and fats (mg/kcal)a 6.593 ± 3.168 6.750 ± 1.988 0.852
Confection (mg/kcal)b 25.62 (17.93–41.11) 23.22 (12.64–42.28) 0.905
Beverages (mg/kcal)b 382.1 (287.8–621.2) 397.5 (230.4–535.7) 0.382
Seasonings and spices (mg/kcal)b 121.6 (81.5–153.7) 144.1 (114.1–183.7) 0.160
Sugar/sweeteners (mg/kcal)b 2.015 (1.277–4.725) 2.127 (1.406–3.024) 0.916

Notes: aData provided as the mean ± standard deviation, analyzed by Student’s t-test. bData provided as the median (interquartile range), analyzed by Mann–Whitney U-test. cFisher’s exact test was used to test the significance of difference in frequency distribution. **Significant difference at p < 0.01.

Abbreviations: SALT, severity of alopecia tool; SFA, saturated fatty acid; MUFA, monounsaturated fatty acid; PUFA, polyunsaturated fatty acid.