| β |
Transmission rate |
day−1
|
Normal (0.00555, 0.000944) |
van Kleef et al., 2016
|
English hospitals (modeling study) |
Mean of point estimates of the daily probability of transmission from colonized patients (0.0037) and infected patients (0.0074) |
| α’ |
Endogenous acquisition rate |
day−1
|
Normal (0.0000253, 0.0000114) |
Durham et al., 2016
|
USA hospitals (modeling study) |
Proxy measure: the estimated daily rate of progression from colonization to infection in hospital patients, divided by the relative risk of progression in patients exposed to antibiotics |
| γ |
Natural clearance rate |
day−1
|
Normal (0.0119, 0.00170) |
Simor et al., 1993
|
Canadian care home |
Fit longitudinal colonization data using exponential decay model |
|
fC
|
Admission fraction (colonized) |
/ |
Binomial (229, 0.048) / 229 |
Barbut, 1996
|
11 French hospitals |
Stool prevalence among asymptomatic patients |
|
r
|
Antibiotic resistance level |
/ |
median 94.3%, (range 93.3–95.4%) |
estimated |
/ |
Cumulative resistance level across simulated antibiotic consumption data and assumed antibiograms |
| ε |
Colonization resistance |
/ |
1–1 / Cauchy (52.85, 1.62) |
estimated |
/ |
From expert opinion |
| η |
Resource competition |
/ |
(1/γ)/(1/γ + Cauchy (121.11, 4.85)) |
estimated |
/ |
From expert opinion |
| ϕ |
Ecological release |
/ |
Cauchy (39.22 0.922) |
estimated |
/ |
From expert opinion |
