Table 2.

Summary of Results of Primary Outcome

	Original Cohort		Matched Cohort		Weighted Cohort		Validation Cohort
	HR (95% CI)	P value	HR (95% CI)	P value	HR (95% CI)	P value	HR (95% CI)	P value
Unadjusted	2.60 (2.03–3.33)	<0.001	2.04 (1.44–2.89)	<0.001	2.00 (1.42–2.82)	<0.001	2.21 (1.68–2.91)	<0.001
Model 1	2.66 (2.07–3.41)	<0.001	2.10 (1.48–2.99)	<0.001	2.05 (1.44–2.91)	<0.001	2.41 (1.83–3.17)	<0.001
Model 2	2.45 (1.89–3.19)	<0.001	2.13 (1.50–3.03)	<0.001	2.22 (1.54–3.22)	<0.001	2.36 (1.79–3.10)	<0.001
Model 3	2.04 (1.56–2.69)	<0.001	2.28 (1.60–3.25)	<0.001	2.40 (1.63–3.52)	<0.001	2.30 (1.75–3.02)	<0.001
Model 4	2.09 (1.58–2.76)	<0.001	2.24 (1.57–3.19)	<0.001	2.77 (2.03–4.58)	<0.001	2.20 (1.67–2.90)	<0.001

Notes: Model 1 adjusted for age, gender, weight, tumor type. Model 2 adjusted for model 1 plus comorbidities and complications. Model 3 adjusted for model 2 plus score system, interventions and Charlson index. Model 4 adjusted for model 3 plus vital signs and laboratory results.

Abbreviations: HR, hazard ratio; 95% CI, 95% confidence index.