TABLE 1.
Representative approved stem cell products on the market
| Region | Trade name | Cell type | Manufacturer | Indications |
|---|---|---|---|---|
| United States | ALLOCORD | HPC cord blood | SSM Cardinal Glennon Children's Medical Center | Hematopoietic and immunologic reconstitution |
| United States | Ducord | HPC cord blood | Duke University School of Medicine | Hematopoietic and immunologic reconstitution |
| United States | Clevecord | HPC cord blood | Cleveland Cord Blood Center | Hematopoietic and immunologic reconstitution |
| United States | Hemacord | HPC cord blood | New York Blood Center, Inc | Hematopoietic and immunologic reconstitution |
| Europe | Alofisel | Allogeneic MSC extracted from adipose tissue | Takeda | Complex anal fistulas in adults with Crohn's disease |
| Europe | Zynteglo | Genetically modified autologous CD34+ cell enriched population that contains HSC | Bluebird bio (Netherlands) B.V. | Beta‐thalassemia |
| Europe | Strimvelis | Autologous CD34+ enriched cell fraction contains genetically modified CD34+ cells | Orchard Therapeutics (Netherlands) BV | Severe combined immunodeficiency |
| Japan | Temcell | Allogeneic MSC from BM | JCR Pharmaceuticals Co. Ltd | Acute GVHD |
| Japan | Stemirac | Autologous MSC from BM | Nipro Corporation | Spinal cord injury |
| South Korea | NeuroNATA‐R | Autologous MSC from BM | CORESTEM | ALS |
| South Korea | Cupistem | Autologous adipose‐derived MSC | Anterogen | Crohn's disease complicated with anal fistul |
| South Korea | Cartistem | Allogeneic derived MSC from UCB | Medipost | Damaged cartilage |
| South Korea | Hearticellgram‐AMI | Autologous MSC from BM | Pharmicell | Aute myocardial infarction |
| Canada/New Zealand | Prochymal (Remestemcel‐L) | Human MSC | Osiris | Acute GVHD in pediatric patients |
| Australia | MPC | Mesenchymal precursor cell | Mesoblast | Repair and regeneration of damaged tissue |
| India | Stempeucel | Autologous MSC from BM | Stempeutics | CLI |
Abbreviations: ALS, amyotrophic lateral sclerosis; BM, bone marrow; CLI, critical limb ischemia; GVHD, graft‐vs‐host disease; HPC, hematopoietic progenitor cell; HSC, hematopoietic stem cells; MSC, mesenchymal stem cells; UCB, umbilical cord blood.