Table 2.
Logistic regression analysis with poor functional outcome as a dependent variable in thalamic ICH (N = 141).
| mRS ≤ 3 (n = 57, 40.43%) | mRS > 3 (n = 84, 59.57%) | Univariate analysis | P value | Multivariable analysis | P value | |
|---|---|---|---|---|---|---|
| OR (95% CI) | OR (95% CI) | |||||
| Age (year) | 62 (54-70) | 67 (59-77) | 1.03 (1.01, 1.06)∗ | 0.018 | 1.06 (1.02, 1.12)∗ | 0.01 |
| Male, N (%) | 38 (66.67%) | 45 (53.57%) | 0.57 (0.28, 1.15) | 0.121 | — | — |
| GCS score | 13 (12-14) | 10 (7-12) | 0.72 (0.62, 0.83)∗ | <0.001 | 0.78 (0.64, 0.95)∗ | 0.016 |
| History of diabetes, N (%) | 4 (7.02%) | 11 (13.10%) | 2.0 (0.64, 7.52) | 0.258 | — | — |
| Current smoking, N (%) | 5 (8.77%) | 8 (9.52%) | 1.09 (0.35, 3.80) | 0.880 | — | — |
| Daily alcohol drinking, N (%) | 1 (1.75%) | 4 (4.76%) | 2.80 (0.40, 55.56) | 0.363 | — | — |
| Antiplatelet medications, N (%) | 2 (3.51%) | 4 (4.76%) | 1.38 (0.26, 10.16) | 0.719 | — | — |
| Systolic BP (mmHg) | 172.49 ± 25.11 | 181.14 ± 25.99 | 1.01 (1.00, 1.03) | 0.054 | 1.02 (0.99, 1.04) | 0.126 |
| Diastolic BP (mmHg) | 100.84 ± 20.27 | 99.38 ± 15.01 | 1.0 (0.98, 1.01) | 0.622 | — | — |
| Symptom onset to baseline CT (hour) | 3 (2-4) | 3 (2-4) | 0.96 (0.78, 1.18) | 0.686 | — | — |
| Baseline ICH volume (ml) | 5.70 ± 2.87 | 11.79 ± 6.59 | 1.38 (1.23, 1.59)∗ | <0.001 | 1.26 (1.08, 1.51)∗ | 0.006 |
| PLIC involvement, N (%) | 11 (19.3%) | 66 (78.57%) | 15.33 (6.85, 37.01)∗ | <0.001 | 11.69 (4.05, 38.27)∗ | <0.001 |
| Intraventricular hemorrhage, N (%) | 32 (56.14%) | 70 (83.33%) | 3.91 (1.82, 8.68)∗ | <0.001 | 1.62 (0.52, 4.89) | 0.383 |
| Hematoma growth# > 3 ml, N (%) | 4 (7.02%) | 21 (25.0%) | 4.42 (1.56, 15.85)∗ | <0.001 | 1.36 (0.28, 7.92) | 0.715 |
| Hematoma growth# > 6 ml, N (%) | 2 (3.51%) | 17 (20.24%) | 6.98 (1.89, 45.22)∗ | 0.012 | 1.44 (0.22, 13.18) | 0.167 |
| Hematoma growth# > 33%, N (%) | 6 (10.53%) | 21 (25.0%) | 2.83 (1.12, 8.19)∗ | 0.037 | 1.66 (0.37, 8.21) | 0.512 |
Abbreviations: OR: odds ratio; CI: confidence interval; ICH: intracerebral hemorrhage; BP: blood pressure; PLIC: posterior limb of internal capsule; GCS: Glasgow Coma Scale. #The independent variables were brought into multivariable logistic regression, respectively. ∗Statistically significant finding. Normally distributed continuous variables are summarized by means ± SD, and skewed continuous variables are presented as medians and interquartile ranges (IQR).