Table 2.
Ten most significant (based on q value) GO and KEGG results from GSEA analysis of Fetal vs. Neonatal differential expression
| GO | ID | Description | setSize | NES | q Values | Count | GeneRatio |
|---|---|---|---|---|---|---|---|
| BP | GO:0048706 | Embryonic skeletal system development | 98 | 2.211 | 1.22E-07 | 41 | 0.418 |
| BP | GO:0048704 | Embryonic skeletal system morphogenesis | 77 | 2.164 | 2.57E-06 | 27 | 0.351 |
| BP | GO:0030239 | Myofibril assembly | 63 | 2.133 | 1.94E-05 | 31 | 0.492 |
| BP | GO:0045214 | Sarcomere organization | 47 | 2.116 | 0.000121 | 25 | 0.532 |
| BP | GO:0010226 | Response to lithium ion | 38 | 2.110 | 0.000178 | 11 | 0.289 |
| BP | GO:0002443 | Leukocyte-media on of immune response | 457 | −2.256 | 5.37E-08 | 144 | 0.315 |
| BP | GO:0050778 | Positive regulation of immune response | 334 | −2.285 | 5.37E-08 | 107 | 0.320 |
| BP | GO:0045087 | Innate immune response | 372 | −2.287 | 5.37E-08 | 144 | 0.387 |
| BP | GO:0002253 | Activation of immune response | 174 | −2.305 | 5.37E-08 | 51 | 0.293 |
| KEGG | ID | Description | setSize | NES | q Values | Count | GeneRatio |
|---|---|---|---|---|---|---|---|
| rno04260 | Cardiac muscle contraction | 70 | 1.775 | 0.006495 | 33 | 0.471 | |
| rno05217 | Basal cell carcinoma | 44 | 1.742 | 0.0082 | 14 | 0.318 | |
| rno04390 | Hippo signaling pathway | 128 | 1.687 | 0.003496 | 28 | 0.219 | |
| rno04080 | Neuroactive ligand-receptor interaction | 192 | 1.672 | 0.000687 | 78 | 0.406 | |
| rno03040 | Spliceosome | 113 | 1.659 | 0.006495 | 79 | 0.699 | |
| rno05152 | Tuberculosis | 137 | −2.018 | 4.61E-06 | 45 | 0.328 | |
| rno04145 | Phagosome | 131 | −2.038 | 2.95E-06 | 48 | 0.366 | |
| rno04621 | NOD-like receptor signaling pathway | 130 | −2.110 | 1.80E-06 | 55 | 0.423 | |
| rno05323 | Rheumatoid arthritis | 65 | −2.192 | 4.61E-06 | 28 | 0.431 | |
| rno04620 | Toll-like receptor signaling pathway | 77 | −2.216 | 2.95E-06 | 24 | 0.312 |
GO, Gene Ontology; GSEA, Gene Set Enrichment Analysis; KEGG, Kyoto Encyclopedia of Genes and Genomes; NES, Normalized Enrichment Score; NOD, nucleotide binding oligomerization domain.