Triglyceride levels and partitioning in Angptl4LivKO mice after overnight fast. A: triglyceride levels on fasted (6 and 18 h) 8- to 12-wk-old male Angptl4fl/fl and Angptl4LivKO mice (means ± SE; n = 8–10 mice). B: clearance of radiolabel from the plasma 1, 5, 10, and 15 min after injection in 8- to 12-wk-old male Angptl4fl/fl and Angptl4LivKO mice fasted for 18 h (means ± SE; n = 7–9). Points represent percentage of radiolabel remaining in the plasma at the indicated time points compared with the 1-min time point (means ± SE). C: uptake of radiolabel (% injected dose/g tissue) into the indicated tissues after 15 min (means ± SE). D: plasma triglyceride levels following tyloxapol (500 mg/kg, intravenous) injection in 8- to 12-wk-old male Angptl4fl/fl and Angptl4LivKO mice following an overnight fast (means ± SE; n = 6/group). E: liver triglyceride content in mice 3 h after tyloxapol injection from mice in E (means ± SE; n = 6/group). **P < 0.01 vs. Angptl4fl/fl mice by Student’s t test. TG, triglyceride.