Ac2-26 (Ac) suppresses the increase in bladder weight during bladder outlet obstruction (BOO) and reduces weight after deobstruction (Deobs). At the end of the described treatment regimens, the bladders were removed and weighed. Data are presented as means ± SE; n = 8, 15, 38, 11, 16, and 20, respectively. *P < 0.05, **P < 0.01, and ***P < 0.001 by ANOVA and a Student-Newman-Keuls test. Con, control.