Figure 9.

Ac2-26 (Ac) does not affect postvoid residual volume (PVR) or voiding efficiency in response to bladder outlet obstruction (BOO) or after deobstruction (Deobs). Animals were subjected to the treatment regimens described elsewhere and subjected to urodynamics. Recordings were analyzed using Med-CMG software (Catamount, St. Albans, VT). Typically, 5−10 individual micturition cycles were quantitated per animal and averaged for n = 1. A: PVR = total amount remaining after voiding (measured by drawing back on the catheter immediately after the last void and measuring any volume recovered). B: voiding efficiency = voided volume divided by (void volume + PVR). Data are presented as means ± SE; n = 15, 13, 8, 7, 9, and 7 for all, respectively. *P < 0.05, **P < 0.01, and ***P < 0.001 by ANOVA and a Student-Newman-Keuls test. Con, control.