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Differential granulomatous response and necrotic lesion development in mice treated with eRAPA alone during chronic Mtb infection. Mice were infected with low dose (∼50-100 CFUs) of Mtb Erdman, and at 7 weeks post Mtb infection, they were either fed a Eudragit diet or an eRAPA diet for 2 weeks. Corresponding mosaic H&E images of lung tissue from each animal in the two groups are shown here. These images were created using Surveyor software with Turboscan by 20× objective imaging.
