Table 3. Hemodynamics before and after aortic valve replacement.

	preop	1-week postop	P value	3-month postop	P value	1-year postop	P value	2-year postop	P value	3-year postop	P value	4-year postop	P value	5-year postop	P value
Number of followers	34	32		28		22		16		15		14		12
Mitral valve area (cm2)	1.80 ± 0.15	2.41 ± 0.40	<0.001	2.42 ± 0.46	<0.001	2.32 ± 0.41	<0.001	2.26 ± 0.58	0.007	2.27 ± 0.57	0.006	2.19 ± 0.62	0.033	2.32 ± 0.48	0.006
Left ventricular ejection fraction (%)	61.1 ± 8.5	59.5 ± 7.9	0.443	62.5 ± 5.6	0.448	63.0 ± 4.6	0.265	64.0 ± 3.4	0.079	61.5 ± 2.1	0.423	62.3 ± 4.4	0.406	62.2. ± 3.7	0.710
Left ventricular end diastolic diameter (mm)	48.6 ± 7.3	45.0 ± 6.2	0.033	42.4 ± 4.7	<0.001	42.3 ± 3.1	<0.001	42.2 ± 3.8	<0.001	44.4 ± 5.2	0.014	41.9 ± 3.8	0.004	42.5 ± 3.8	0.027
Left ventricular end systolic diameter (mm)	32.5 ± 7.0	31.2 ± 5.2	0.412	27.8 ± 3.2	0.002	27.9 ± 2.8	0.001	27.7 ± 3.2	0.001	29.3 ± 3.7	0.043	26.7 ± 2.9	<0.001	28.3 ± 2.9	0.109
Left ventricular mass (g)	253 ± 87	225 ± 72	0.155	187 ± 52	0.001	175 ± 47	0.001	162 ± 41	<0.001	169 ± 37	<0.001	163 ± 34	0.001	161 ± 47	0.001
Left atrial diameter (mm)	45.3 ± 7.6	42.9 ± 6.9	0.184	42.7 ± 6.9	0.162	41.3 ± 6.0	0.038	42.8 ± 4.7	0.204	45.4 ± 6.1	0.702	43.1 ± 6.4	0.368	41.8 ± 6.0	0.235
E/e' (lateral)	19.3 ± 10.4	22.5 ± 12.0	0.308	20.0 ± 9.9	0.804	19.9 ± 10.6	0.837	19.2 ± 7.3	0.983	25.2 ± 12.9	0.126	24.3 ± 8.3	0.226	28.7 ± 9.9	0.040
E/e' (septal)	25.7 ± 14.3	28.0 ± 11.9	0.529	29.2 ± 14.5	0.399	28.0 ± 14.5	0.572	29.6 ± 9.2	0.321	30.7 ± 10.4	0.264	29.0 ± 9.6	0.573	34.0 ± 9.3	0.158
Aortic valve
Aortic valve area (cm2)	0.79 ± 0.19	1.72 ± 0.31	<0.001	1.72 ± 0.26	<0.001	1.80 ± 0.25	<0.001	1.71 ± 0.26	<0.001	1.71 ± 0.27	<0.001	1.71 ± 0.31	<0.001	1.67 ± 0.23	<0.001
Indexed aortic valve area (cm2/m2)	0.56 ± 0.13	1.23 ± 0.23	<0.001	1.23 ± 0.23	<0.001	1.30 ± 0.21	<0.001	1.21 ± 0.19	<0.001	1.21 ± 0.20	<0.001	1.20 ± 0.23	<0.001	1.18 ± 0.17	<0.001
Peak velocity (m/s)	4.8 ± 0.8	2.5 ± 0.6	<0.001	2.4 ± 0.4	<0.001	2.2 ± 0.4	<0.001	2.3 ± 0.5	<0.001	2.1 ± 0.4	<0.001	2.3 ± 0.7	<0.001	2.6 ± 0.9	<0.001
Peak pressure gradient (mmHg)	92.8 ± 30.6	26.1 ± 13.2	<0.001	23.4 ± 8.5	<0.001	21.6 ± 7.3	<0.001	22.4 ± 9.6	<0.001	18.9 ± 7.4	<0.001	22.1 ± 13.1	<0.001	28.9 ± 19.6	<0.001
Mean pressure gradient (mmHg)	51.4 ± 18.5	12.1 ± 6.1	<0.001	10.9 ± 4.0	<0.001	10.2 ± 3.3	<0.001	10.7 ± 5.6	<0.001	9.1 ± 3.0	<0.001	11.2 ± 7.2	<0.001	14.1 ± 10.1	<0.001