Table 3.
Unique peptides of LXR variants
| LXR | Also, recognize | Peptide mass | Amino acid position (based on LXRa1 structure) |
Exon | Unique peptides (after trypsin digestion) | |
|---|---|---|---|---|---|---|
| Start | End | |||||
| α1 | α2 | 1607.8137 | 1 | 15 | 2 | MSLWLGAPVPDIPPD |
| 1348.7140 | 293 | 300 | 6 | SAIEVMLLETSR | ||
| α2 | α5 | 1148.6343 | 235,236-297 | 300 | 5/7 | VT-VMLLETSR |
| α3 | α5 | 2307.1761 | 46 | 69 | 3 | MPHSAGGTAGVGLEAAEPTALLTR |
| α4 | – | 1550.7090 | −14 | −1 | -1d | MQQTSWNPLGGTCK |
| 554.3045 | −19 | −15 | -1d | QPPGR | ||
| XP_0243040XXX | – | 2942.3842 | Additional 64 amino acids due to the presence of a retained intron in between exon 6 and 7 | Exon -7a | GEAEWDYLWEGPPDIELGEP NLLGSR | |
| 1170.5538 | DEENRPPWK | |||||
| 1005.4669 | EVAGEGQGMK | |||||
| 741.3890 | TSPPSPR | |||||
| 590.3079 | RPCSK | |||||
| 510.2381 | FAACV | |||||
| β1 | 1423.7328 | 248 | 260 | Exon6/ | VTPWPLGADPQSR | |
| 1475.7892 | 268 | 279 | exon7abc | FAHFTELAIISVQ | ||
| β3 | 1021.5564 | 249–280 | 286 | Exon6/exon7b | V-TEIVDFAK | |
| β4 | 545.3405 | 249–293 | 299 | Exon6/Exon 7c | V-TLGREDQ | |
Amino acids position number based on α1 and/or β1 amino acid numbering position. Amino acid numbering position with “-” indicates the additional amino acid(s) coming before α1 and/or β1’s amino acid position number 1. The numerical exons represent the first discovered exons. The numerical exons followed with alphabets represent the later discovered exons.