Table 1.
Characteristics of subjects across LS7 categories.
| LS7 categories |
|||||
|---|---|---|---|---|---|
| Characteristics | Poor (n = 279) | Intermediate (n = 1367) | Optimal (n = 341) | Total (n = 1987) | p value |
|
| |||||
| Age (years), mean (SD) | 74.97 (5.76) | 75.52 (5.96) | 74.87 (6.24) | 75.33 (5.98) | 0.112 |
| Gender, n (%) | 0.002 | ||||
| Male | 72 (25.81) | 429 (31.38) | 132 (38.71) | 633 (31.86) | |
| Female | 207 (74.19) | 938 (68.62) | 209 (61.29) | 1354 (68.14) | |
| Race/ethnicity, n (%) | < 0.001 | ||||
| White | 56 (20.07) | 350 (25.60) | 155 (45.45) | 561 (28.23) | |
| Black | 93 (33.33) | 408 (29.85) | 84 (24.63) | 585 (29.44) | |
| Hispanic | 127 (45.52) | 579 (42.36) | 96 (28.15) | 802 (40.36) | |
| Others | 3 (1.08) | 30 (2.19) | 6 (1.76) | 39 (1.96) | |
| Education duration (years), mean (SD) | 9.99 (4.92) | 10.63 (4.91) | 12.97 (4.62) | 10.94 (4.95) | < 0.001 |
| Cohort wave, n (%) | < 0.001 | ||||
| 1992 cohort | 50 (17.92) | 165 (12.07) | 32 (9.38) | 247 (12.43) | |
| 1999 cohort | 149 (53.41) | 694 (50.77) | 120 (35.19) | 963 (48.47) | |
| 2009 cohort | 80 (28.67) | 508 (37.16) | 189 (55.43) | 777 (39.10) | |
| Dietary calories (kcal), mean (SD) | 1380.59 (568.31) | 1403.39 (500.04) | 1391.20 (447.96) | 1398.09 (501.61) | 0.757 |
| Depression, n (%) | 0.008 | ||||
| No | 189 (67.74) | 1019 (74.54) | 268 (78.59) | 1476 (74.28) | |
| Yes | 90 (32.26) | 348 (25.46) | 73 (21.41) | 511 (25.72) | |
| History of hypertension, n (%) | < 0.001 | ||||
| No | 26 (9.32) | 185 (13.53) | 116 (34.02) | 327 (16.46) | |
| Yes | 253 (90.68) | 1182 (86.47) | 225 (65.98) | 1660 (83.54) | |
| History of diabetes, n (%) | < 0.001 | ||||
| No | 127 (45.52) | 966 (70.67) | 312 (91.50) | 1405 (70.71) | |
| Yes | 152 (54.48) | 401 (29.33) | 29 (8.50) | 582 (29.29) | |
| History of heart diseases, n (%) | 0.001 | ||||
| No | 144 (51.61) | 739 (54.06) | 219 (64.22) | 1102 (55.46) | |
| Yes | 135 (48.39) | 628 (45.94) | 122 (35.78) | 885 (44.54) | |
| APOE-ε4 allele, n (%) | 0.392 | ||||
| Noncarrier | 205 (73.48) | 1016 (74.32) | 241 (70.67) | 1462 (73.58) | |
| Carrier | 74 (26.52) | 351 (25.68) | 100 (29.33) | 525 (26.42) | |
| LS7 scores, mean (SD) | 4.42 (0.82) | 7.49 (1.06) | 10.57 (0.82) | 7.59 (1.98) | < 0.001 |
| Incident dementia, n (%) | 0.003 | ||||
| No | 224 (80.29) | 1165 (85.22) | 307 (90.03) | 1696 (85.35) | |
| Yes | 55 (19.71) | 202 (14.78) | 34 (9.97) | 291 (14.65) | |
Abbreviations: APOE-ε4, apolipoprotein E genotype ε4; LS7, Life’s Simple 7; SD, standard deviation; %, proportion.