TABLE 1.
Off-label request patient characteristics and univariate logistic regression analysis for treatment initiation (n = 708).
| Characteristic | Total n (%) | Treatment initiated n = 583 n (%) | Treatment not initiated n = 125 n (%) | Odds ratio | 95% CI for odds ratio lower upper | p-value |
| Age (years) Median, Mean | 64, 62 (19–95) | 64, 62 (19–95) | 65, 64 (27–89) | 1.012 | 0.997–1.028 | 0.114 |
| (range) | ||||||
| Gender Male | 297 (42) | 243 (42) | 54 (43) | 1.064 | 0.720–1.572 | 0.755 |
| Female | 411 (58) | 340 (58) | 71 (57) | |||
| Children | 532 (75) | 433 (74) | 99 (79) | 1.319 | 0.824–2.111 | 0.248 |
| Health insurer | ||||||
| Clalit | 539 (76) | 439 (75) | 100 (80) | 0.762 | 0.473–1.228 | 0.264 |
| Maccabi | 99 (14) | 85 (14.4) | 14 (11) | 1.353 | 0.742–2.470 | 0.324 |
| Meuhedet | 39 (5.5) | 30 (5) | 9 (7) | 0.699 | 0.323–1.512 | 0.363 |
| Leumit | 27 (4) | 25 (5) | 2 (2) | 2.755 | 0.644–11.787 | 0.172 |
| Tourist/Not insured | 4 (0.5) | 4 (0.5) | 0 (0) | NA | NA | NA |
| Supplementary public insurance | ||||||
| None | 228 (32) | 195 (33) | 33 (26) | 1.401 | 0.908–2.161 | 0.127 |
| Basic | 226 (32) | 183 (32) | 43 (34) | 0.872 | 0.508–1.312 | 0.513 |
| Premium | 254 (36) | 205 (35) | 49 (40) | 0.841 | 0.565–1.251 | 0.393 |
| SES Median Decile | 7 | 7 | 7 | 1.078 | 0.961–1.210 | 0.198 |
| Decile 1–3 | 59 (8) | 50 (9) | 9 (7) | |||
| Decile 8–10 | 264 (37) | 217 (37) | 47 (38) | |||
| Distanceto RMC (km) Median, Mean (range) | 18.5, 30 (3–344) | 18.5, 30 (3–344) | 15, 29 (3–344) | 0.999 | 0.994–1.004 | 0.779 |
SES, Socioeconomic status; RMC, Rabin Medical Center; km, kilometers.
Gender is for Males compared to Females.