TABLE 1.
Summary of samples investigated. The table shows the protein and lipid concentration, lipid composition in model membranes and deuteration level of the buffer used in the scattering experiment (M = mol/L).
| Sample number | Protein type and concentration | Buffer composition | Lipid composition | Lipid to protein molar ratio |
|---|---|---|---|---|
| 1 | d-αS, 110 μM | 100% H2O | — | — |
| 2 | d-αS, 110 μM | 100% H2O | DOPC/DOPS | 1 |
| 3 | d-αS, 110 μM | 100% H2O | DOPC/GM1 | 1 |
| 4 | d-αS, 110 μM | 100% H2O | DOPC/GM3 | 1 |
| 5 | h-αS, 140 μM | 100% D2O | — | — |
| 6 | h-αS, 140 μM | 100% D2O | DOPC/DOPS | 0.4 |
| 7 | h-αS, 140 μM | 100% D2O | DOPC/GM1 | 0.4 |
| 8 | h-αS, 140 μM | 100% D2O | — | — |
| 9 | h-αS, 140 μM | 100% D2O | DMPC/DMPS | 1 |
| 10 | h-αS, 140 μM | 100% D2O | DMPC/DMPS | 5 |
| 11 | h-αS, 140 μM | 100% D2O | DMPC/DMPS | 15 |
| 12 | h-αS, 140 μM | 100% D2O | POPC/POPS | 1 |
| 13 | h-αS, 140 μM | 100% D2O | POPC/POPS | 2 |
| 14 | h-αS, 140 μM | 100% D2O | POPC/POPS | 5 |
| 15 | h-αS, 140 μM | 100% D2O | POPC/GM1 | 1 |
| 16 | h-αS, 140 μM | 100% D2O | POPC/GM1 | 2 |
| 17 | h-αS, 140 μM | 100% D2O | POPC/GM1 | 5 |
| 18 | h-αS, 140 μM | 100% D2O | POPC/GM3 | 1 |
| 19 | h-αS, 140 μM | 100% D2O | POPC/GM3 | 2 |