Table 2.

ROC of plasma exosomal glycoproteins as biomarkers for early diagnosis of CRC.

marker	FBG	β2-GP1	FBG+β2-GP1	CEA	CA19-9
AUC (95% CI)	0.871	0.834	0.915	0.723	0.614
	(0.786–0.914)	(0.734–0.901)	0.845–0.987	(0.679–0.853)	(0.543–0.715)
Cutoff	18.6 ng/L	30.6 ng/L		4.7 ng/ml	27.0 U/ml
Sensitivity (%)	68.35	71.55	63.84	48.43	53.67
Specificity (%)	86.27	85.51	93.54	81.23	83.14
Positive likelihood ratio (%)	93.22	91.15	96.2	79.25	77.31
Negative likelihood ratio (%)	73.26	70.11	75.6	54.32	51.28