Table 3.
Detection of the Beijing 1071-32-cluster by the developed PCR assay in local collections.
| Country, region, years | Beijing | Beijing 1071-32 |
|---|---|---|
| Russia, Northwest, CПб 1996–2020 | 835 | 22 |
| Russia, Northwest, Karelia, 2014 | 43 | 6 |
| Russia, Northwest, Pskov, 2015, 2018 | 85 | 3 |
| Russia, Northwest, Kaliningrad, 2015 | 46 | 1 |
| Russia, Northwest, Komi, 2017 | 73 | 1 |
| Russia, Northwest, Vologda, 2018 | 51 | 0 |
| Russia, Northwest, Murmansk, 2017 | 32 | 0 |
| Russia. Siberia, Omsk, 2008–2019 | 372 | 37 |
| Russia, Siberia, Irkutsk, 2014–2015 | 147 | 2 |
| Russia, Ural, Yamalo-Nenets, 2017 | 101 | 1 |
| Russia, Ural, Yekaterinburg, 2019–2020 | 85 | 2 |
| Russia, Far East, Yakutia, 2012 | 67 | 1 |
| Albania, 2007–2011 | 5 | 1 |
| Greece, 2008–2011 | 19 | 3 |
| Estonia, 1999 and 2014 | 91 | 0 |
| Belarus, 2004 | 50 | 0 |
| Kazakhstan, 2010 | 109 | 0 |
| China, 2004 | 45 | 0 |
| Vietnam, 2005 | 37 | 0 |
| Japan, 2003–2005 | 71 | 0 |
| Brazil, 2001–2007 | 11 | 0 |
| Total | 2375 | 80 |
Beijing genotype was detected using spoligotyping, or PCR targeting dnaA-dnaN::IS6110 (Mokrousov et al., 2014) or based on VNTR-clustering. Beijing 1071-32-cluster was detected by real-time PCR analysis of SNPs in Rv0144, Rv0373c, and Rv0334 as described in this study.
Geographic locations are shown on Fig. 3.