Table 2.
Factors associated with the diagnosis of NAION versus NTG.
| Univariable | Multivariable | |||||
|---|---|---|---|---|---|---|
| Variables | OR | 95% CI | p value | OR | 95% CI | p value |
| Age (per 1 yr older) | 1.096 | 1.008–1.192 | 0.032 | 1.057 | 0.906–1.234 | 0.479 |
| Refractive error (per 1 D higher) | 1.360 | 0.915–2.021 | 0.129 | |||
| Hypertension, presence | 1.818 | 0.388–8.514 | 0.448 | |||
| Diabetes, presence | 1.562 | 0.240–10.187 | 0.641 | |||
| Hyperlipidemia, presence | 0.460 | 0.077–2.753 | 0.395 | |||
| Intraocular pressure (per 1 mmHg higher) | 1.099 | 0.914–1.321 | 0.315 | |||
| Peripapillary RNFL thickness (per 1 μm thicker) | 1.005 | 0.942–1.072 | 0.888 | |||
| Peripapillary vessel density (per 1% higher) | 0.890 | 0.802–0.989 | 0.030 | 0.940 | 0.772–1.144 | 0.534 |
| Choroidal vessel density of β-PPA (per 1% higher) | 1.019 | 0.888–1.170 | 0.787 | |||
| β-PPA area (per 0.01 mm2 larger) | 0.998 | 0.987–1.009 | 0.729 | |||
| CMvD area (per 0.01 mm2 larger) | 1.123 | 1.023–1.232 | 0.014 | 1.181 | 1.021–1.366 | 0.025 |
| CMvD angular width (per 1° wider) | 1.059 | 1.020–1.100 | 0.003 | 1.013 | 0.958–1.070 | 0.660 |
| CMvD angular location (per 1° away from temporal area) | 0.938 | 0.901–0.976 | 0.002 | 0.904 | 0.838–0.975 | 0.009 |
β-PPA β-zone peripapillary atrophy, CI Confidence interval, MvD Choroidal microvasculature dropout, NAION Nonarteritic anterior ischemic optic neuropathy, NTG Normal-tension glaucoma, OR Odds ratio, RNFL Retinal nerve fiber layer.
Boldface p values indicate statistical significance.