Figure 5.
Vaccination with the surface engineered exosomes was not able to elicit exosome-induced memory T cell responses in vivo. Groups of vaccinated mice were sacrificed either 3 or 6 days post-infection (dpi). Cells from the lungs were stimulated with (A) M187–195 or (B) NS161–75 peptides for 72 h. An ELISA analysis for IFN-γ was performed on the cell culture supernatants. Data are presented as means ± SEM. (A) *p < 0.05, **p < 0.01 as determined by two-way ANOVA and Šídák's multiple comparisons test. (B) *p < 0.05 as determined by two-way ANOVA and Tukey's multiple comparisons test.