Table 1.
Characteristics of the participants in the two stages.
| Characteristics | First stage (N = 886) | Second stage (N = 1,128) | p-value c | ||||||
|---|---|---|---|---|---|---|---|---|---|
| All | Positive | Negative | p-value b | All | Positive | Negative | p-value b | ||
| Biopsy result, N (%) | 885 | 401 (45.31) | 484 (54.69) | 1124 | 462 (41.10) | 662 (58.90) | 0.68 | ||
| p2PSA a , median (IQR), pg/ml | 22.14 (49.56) | 62.98 (312.52) | 15.14 (13.97) | 2.02 × 10−68 | 22.92 (40.02) | 47.22 (181.97) | 17.88 (16.73) | 1.65 × 10−52 | 0.87 |
| Age, mean ± SD, year | 68.26 ± 9.64 | 70.87 ± 8.38 | 66.10 ± 10.05 | 1.17 × 10−13 | 67.73 ± 8.51 | 70.78 ± 7.92 | 65.60 ± 8.30 | 8.81 × 10−24 | 0.34 |
p2PSA [–2],proPSA; IQR, interquartile range; SD, standard deviation.
a
p2PSA was measured in picograms per milliliter. Data were log-transformed for genome-wide association study (GWAS) analysis.
b
P-values for the difference between positive and negative, Mann–Whitney U test for p2PSA, and t-test for age.
c
P-values for the difference between two stages, chi-square test for the biopsy results, Mann–Whitney U test for p2PSA, and t-test for age.