Table 2.
Non-coding RNAs in the etiology and control of HIV/AIDS.
| Role in HIV Infection | Non-coding RNA | Action | Reference |
|---|---|---|---|
| Etiology | miR-873 | Activation of HIV transcription | (52, 53) |
| MALAT1 | (53, 54) | ||
| HEAL | (53, 55) | ||
| LINC01426 | (53, 56) | ||
| LINC00173 | (57) | ||
| NEAT1 | Inhibition of HIV transcription | (53, 58, 59) | |
| NRON | (60, 61) | ||
| GAS5 | (52) | ||
| lincRNA-p21 | (62, 63) | ||
| Diagnosis | miR-146b-5p | Downregulation in B and T-lymphocytes | (64, 65) |
| miR-223 | |||
| miR-150 | |||
| miR-16 | |||
| miR-191 | |||
| lncRNA NEAT1 | Presence in the plasma | ||
| Therapeutic targets | MALAT1 | Promotion of HIV transcription, | (63) |
| HEAL | Action in HIV-1 latency | (53) | |
| SAF | Resistance of HIV-1–infected macrophages to activation of apoptotic caspases | (66) | |
| lincRNA-p21 | HIV-1–infected macrophages | (62) | |
| NEAT1 | Dissemination of HIV-1 | (58, 59) | |
| GAS5 | Suppression of miR-873 | (52) | |
| NRON | HIV-1 latency | (60, 61) | |
| LINC00173 | Regulation of cytokine levels in T cells | (57) |