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. 2021 Nov 1;12(11):1041. doi: 10.1038/s41419-021-04337-9

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© The Author(s) 2021

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Fig. 1 — A Illustration of the 3D structure of RyR2 viewed from the cytoplasmic side and adapted from Peng et al. [35]. B Domain organization of the RyR2. NTD N-terminal domain, SPRY splA kinase and RyR domain, P1/P2 RyR repeat domain rich in phosphorylation sites, HD1/HD2 Helical domain.