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. 2021 Nov 1;11:21355. doi: 10.1038/s41598-021-00888-1

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Classification of field wMel Ae. aegypti according to their Wolbachia density by LAMP, MALDI-TOF MS protein profiling, and MALDI-TOF MS coupled to CNN. (a): results obtained with LAMP assay. (b): results obtained with MALDI-TOF MS protein profiling. (c): results obtained with MALDI-TOF MS coupled to CNN. Each dot represents one field Ae. aegypti detected as positive for Wolbachia by qPCR (n = 56). Y axis corresponds to the decimal logarithm of Wolbachia density according to the qPCR results. In the X-axis, wMel corresponds to the true positive results, equivocal (only for LAMP) and WT correspond to the false negative results.