Table 3.

Comparison of LAMP, MALDI-TOF MS profiling, and MALDI-TOF MS coupled to CNN performances when analyzing field-mosquitoes (n = 194).

Technic	Se [95% CI]	Sp [95% CI]	PPV [95% CI]	NPV [95% CI]	Accuracy [95% CI]
LAMP	80% [68–90]	100% [97–100]	100%	93% [88–95]	94% [90–97]
MALDI-TOF	77% [64–87]	99% [96–100]	98% [86–100]	91% [87–94]	93% [88—96]
CNN on MALDI-TOF	93% [89–96]	99% [97–100]	96% [94–99]	97% [95–99]	97% [94–99]

Abbreviations: Se, sensitivity; Sp, specificity; PPV, positive predictive value; NPV, negative predictive value.

The performance indicators were calculated in comparison to the results of the gold standard qPCR technique.