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. 2021 Nov 1;7:329. doi: 10.1038/s41420-021-00724-5

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© The Author(s) 2021, corrected publication 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — A FTO was detected by western blotting after FTO knockdown in T24 and UM-UC-3 cells. B The m6A levels were measured in FTO-knockdown T24 and UM-UC-3 cells. C CCK-8 assay showed that FTO knockdown inhibited cell proliferation. D Transwell migration and invasion assays after FTO knockdown at a 100× magnification. Scale bars represent 100 μm. E Cell-cycle analysis was performed in FTO-knockdown T24 and UM-UC-3 cells using flow cytometry. F Image of tumours collected from nude mice. The tumour growth curve and tumour weight were measured in the FTO knockdown group and the control group. The results are presented as mean ± standard deviation (SD). *P < 0.05, **P < 0.01, ***P < 0.001.