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. 2021 Nov 1;12:6276. doi: 10.1038/s41467-021-26502-6

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a Heatmap shows differentially expressed proteins (p < 0.05 and Log2 FC >1) and significantly enriched pathways (Reactome) by subtype for TNBC tumors in CPTAC. Balloon plots show integrated pathway analysis of RNA, protein, and phosphoprotein log fold change values for genes/proteins from CPTAC TNBC tumors demonstrating subtype-specific differences in b DNA repair/cell cycle, c PI3K/mTOR, d EGFR/MAPK, and e antigen presentation pathways. FDR represents the false discovery rate that the normalized enrichment score represents a false-positive finding.