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Efficacy of isofagomine and noeuromycin against TcdA and TcdB-induced cell rounding of Vero cells.
| C. difficile toxin and iminosugar | Calculated IC50 (μM) |
|---|---|
| TcdA + Isofagomine | 5.5 ± 1.5 |
| TcdA + Noeuromycin | 9.6 ± 3.3 |
| TcdB + Isofagomine | 8.3 ± 3.6 |
| TcdB + Noeuromycin | 13.6 ± 5.6 |
The data represents the mean of three biological replicates ± SEM.
Source data are provided as a Source Data file.
