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. 2021 Nov 1;4:1244. doi: 10.1038/s42003-021-02751-5

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 9 — a Top view of electrode implantation. Spheres colored in red and orange represent the centers of regions in the EZ and PZ, respectively. b Structural connectivity in log scale. c Gain matrix, transformation matrix from source-to-sensor space, in log scale. d Simulated local field potential (x₁(t) + x₂(t)) depicting the seizure propagation pattern. e Simulated SEEG activity from eight channels. EZ, epileptogenic zone; PZ, propagation zone; SEEG, stereotactic electroencephalography.