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. 2021 Nov 1;11:21354. doi: 10.1038/s41598-021-98642-0

Figure 2.

Figure 2

Heat map of selected metabolite levels according to major metabolic pathways. Measured metabolites were classified according to their primary metabolic pathways (refer to Supplementary Table 2). For each pathway and treatment group, the log-median-QC normalized value was used. Red—maximum levels, blue—minimum levels. Met—attached 5 mM metformin treated cells, MetDG—attached 5 mM metformin + 0.6 mM 2DG treated cells, HiDG—attached 4.8 mM 2DG treated cells , CTRL—attached untreated control cells, poly-HEMA—floating untreated cells grown on poly-HEMA, FloatMetDG—floating detached 5 mM metformin + 0.6 mM 2DG treated cells, LoDG—0.6 mM 2DG treated attached cells, FloatHiDG—floating detached 4.8 mM 2DG treated cells.