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. 2021 Nov 1;11:21366. doi: 10.1038/s41598-021-00694-9

Table 3.

Multivariable analysis of risk factors for decreased GFR and CKDU.

Risk factors All age Age < 70
eGFR < 60 eGFR < 60 CKDu1 CKDu2
Odds ratio (95% CI) Odds ratio (95% CI) Odds ratio (95% CI) Odds ratio (95% CI)
Age (per 10 year) 3.17 (3.14–3.21) 3.52 (3.42–3.62) 3.35 (3.42–3.50) 3.39 (3.23–3.55)
Women (men = reference) 1.70 (1.24–2.34) 1.65 (1.17–2.32) 2.41 (1.49–3.89) 2.41 (1.49–3.89)
Diabetes (Y versus N) 2.01 (1.68–2.40) 1.67 (1.32–2.10) na na
Hypertension (Y versus N) 2.05 (1.76–2.38) 2.34 (2.01–2.72) na na
Gout (Yes versus No) 5.69 (4.63–7.00) 5.58 (4.43–7.02) 3.77 (2.43–5.84) 4.06 (2.65–6.23)
Kidney stones (Y versus N) 2.09 (1.52–2.89) 2.86 (2.18–3.75) 6.33 (4.24–9.46) 6.72 (4.43–10.19)
Painkillers (regular versus less) 2.02 (1.51–2.72) 1.84 (1.26–2.69) 2.67 (1.16–6.13) 2.86 (1.23–6.66)
Rural (urban = reference) 1.07 (0.92–1.241) 1.16 (0.98–1.37) 1.66 (1.19–2.32) 1.88 (1.32–2.68)
Laborer/agriculture (other occupations = reference) 1.06 (0.89–1.27) 0.93 (0.77–1.12) 1.54 (1.08–2.20) 1.45 (1.02–2.05)
BMI (18.5–24.9 = reference)
< 18.5 1.27 (0.91–1.78) 1.56 (1.04–2.36) 1.86 (1.07–3.21) 1.94 (1.12–3.38)
25–29.9 0.87 (0.75–1.01) 0.79 (0.65–0.97) 0.95 (0.65–1.39) 0.96 (0.64–1.44)
≥ 30 1.03 (0.80–1.33) 0.95 (0.72–1.26) 0.65 (0.33–1.28) 0.69 (0.35–1.37)
Current smoking (non-smoker = reference) 1.14 (0.84–1.55) 1.14 (0.82–1.58) 1.34 (0.85–2.14) 1.36 (0.85–2.18
Cardiovascular disease (Y versus N) 1.19 (0.88–1.61) 1.26 (0.90–1.77) 1.11 (0.44–2.76) 1.16 (0.46–2.95)
Herbal medications (Y versus N) 0.89 (0.79–1.01) 0.89 (0.76–1.04) 0.79 (0.56–1.12) 0.68 (0.46–1.01)

Bold represent statistical significance; Risk compared to no CKD.