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. 2021 Sep 28;27(11):gaab062. doi: 10.1093/molehr/gaab062

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© The Author(s) 2021. Published by Oxford University Press on behalf of European Society of Human Reproduction and Embryology.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 4. — The zygote centrosomal composition is biparentally inherited during fertilization. (A) Venn diagram showing overlap of 48 centrosomal proteins in the human oocyte and sperm. (B) Representative IF image of an in vitro matured metaphase II oocyte stained for pericentrin, tubulin and DNA. Scale: 10 μm. N = 10 oocytes. (C) IF images of abnormally fertilized human embryos at D + 2 stained for pericentrin, tubulin and DNA. Scale: 10 μm. N = 13 fertilized human embryos. (D) Pericentrin, tubulin and DNA staining of a D + 2 parthenogenetically activated human oocyte. Scale: 20 μm. N = 6 activated human oocytes.