Table 2. The risk factors for NAFLD.
Risk Factor | Univariate | Multivariate | |||||
---|---|---|---|---|---|---|---|
OR | p * | 95% CI | OR | p † | 95% CI | ||
BMI (kg/m2) | |||||||
≥ 25 | 3.526 | < 0.001 | 1.780–6.985 | 2.270 | 0.047 | 1.012–5.093 | |
< 25 | |||||||
Menopause | 0.760 | 0.430 | 0.380–1.520 | ||||
Pre-menopause | |||||||
Waist (cm) | |||||||
≥ 80 | 6.111 | < 0.001 | 2.407–15.518 | 4.138 | 0.009 | 1.428–11.992 | |
< 80 | |||||||
Cholesterol (mg/dL) | |||||||
≥ 200 | 1.253 | 0.462 | 0.654–2.402 | ||||
< 200 | |||||||
Triglyceride (mg/dL) | |||||||
≥ 150 | 2.793 | 0.003 | 1.405–5.551 | 2.253 | 0.036 | 1.054–4.865 | |
< 150 | |||||||
HDL-C (mg/dL) | |||||||
≤ 50 | 2.245 | 0.016 | 1.158–4.355 | 1.295 | 0.521 | 0.587–2.858 | |
> 50 | |||||||
LDL-C (mg/dL) | |||||||
≥ 150 | 0.491 | 0.040 | 0.248–0.974 | 0.309 | 0.005 | 0.137–0.697 | |
< 150 | |||||||
Fasting glucose (mg/dL) | |||||||
≥ 100 | 0.970 | 0.93 | 0.489–1.924 | ||||
< 100 | |||||||
Hypertension | |||||||
Yes | 1.213 | 0.561 | 0.633–2.325 | ||||
No | |||||||
Hormone treatment | |||||||
Tam | |||||||
AI | 0.695 | 0.309 | 0.344–1.404 | ||||
Hormone treatment | |||||||
Tam | |||||||
Tam + AI | 0.825 | 0.424 | 0.338–2.012 |
NAFLD = non-alcoholic fatty liver disease; OR = odd ratio; CI = confidence interval; BMI = body mass index; HDL-C = high density lipoprotein cholesterol; LDL-C = low density lipoprotein cholesterol; Tam = tamoxifen; AI = aromatase inhibitor; Tam + AI = tamoxifen for 2 years followed by AI.
*Footnote mark is calculated with Pearson χ2 test; †calculated by regression logistic, method backward LR; p < 0.05 is considered as statistically significant (bold-faced).