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. 2021 Sep 9;24(5):417–427. doi: 10.4048/jbc.2021.24.e41

Table 2. The risk factors for NAFLD.

Risk Factor Univariate Multivariate
OR p * 95% CI OR p 95% CI
BMI (kg/m2)
≥ 25 3.526 < 0.001 1.780–6.985 2.270 0.047 1.012–5.093
< 25
Menopause 0.760 0.430 0.380–1.520
Pre-menopause
Waist (cm)
≥ 80 6.111 < 0.001 2.407–15.518 4.138 0.009 1.428–11.992
< 80
Cholesterol (mg/dL)
≥ 200 1.253 0.462 0.654–2.402
< 200
Triglyceride (mg/dL)
≥ 150 2.793 0.003 1.405–5.551 2.253 0.036 1.054–4.865
< 150
HDL-C (mg/dL)
≤ 50 2.245 0.016 1.158–4.355 1.295 0.521 0.587–2.858
> 50
LDL-C (mg/dL)
≥ 150 0.491 0.040 0.248–0.974 0.309 0.005 0.137–0.697
< 150
Fasting glucose (mg/dL)
≥ 100 0.970 0.93 0.489–1.924
< 100
Hypertension
Yes 1.213 0.561 0.633–2.325
No
Hormone treatment
Tam
AI 0.695 0.309 0.344–1.404
Hormone treatment
Tam
Tam + AI 0.825 0.424 0.338–2.012

NAFLD = non-alcoholic fatty liver disease; OR = odd ratio; CI = confidence interval; BMI = body mass index; HDL-C = high density lipoprotein cholesterol; LDL-C = low density lipoprotein cholesterol; Tam = tamoxifen; AI = aromatase inhibitor; Tam + AI = tamoxifen for 2 years followed by AI.

*Footnote mark is calculated with Pearson χ2 test; calculated by regression logistic, method backward LR; p < 0.05 is considered as statistically significant (bold-faced).