PCA of the condition comparisons. PCA of the gene expression profiles was done across all conditions, including artificial CSF (aCSF), rabbit CSF (rCSF), human CSF (hCSF), capsule-inducing medium (CAP), and yeast peptone dextrose broth (YPD) (A); between the in vivo CSF (human CSF and rabbit CSF) and YPD samples (B); between the rabbit CSF and human CSF samples (C); and between the rabbit CSF samples on day 4 and day 1 (D).